Your companion for learning cardiovascular
physiology & hemodynamics through the combined power of a novel e-textbook series and a dynamic, interactive simulation.

Harvi - PVLoops LLC

The Family of Apps

Be sure to look for the family of Harvi Apps designed to meet the different needs of students, educators and researchers that will be available soon on the App Store.



harvi student

Harvi Student

harvi lecture

Harvi Lecture coming soon

harvi simulation

Harvi Sim
coming soon

The Harvi textbook series covers a full range of topics related to cardiovascular physiology and hemodynamics.

Comprehensive Textbook of hemodynamics with emphasis on the utility of pressure-volume analysis
Real time simulation displaying pressure-volume loops with interactive controls that show you the impact of system peramerters
You are in control: Customize your learning experience with easy-to-use navigation buttons
Pressing a Try it Now button will activate a didactic interactive pop-up window
Consise chapters that cover a broad range of hemodynamics topics in health and disease
Dynamic tracings of cardiovascular perameters integrated with the text

Many of these topics are easily explained and understood by examining ventricular and atrial pressure-volume diagrams. The text will make extensive use of that approach to illustrate key points.

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The Four Part Series

Here's more information on the four part series of Harvi textbooks

Part I. Basic Physiological Principles

  1. Introduction
  2. The Cardiac Cycle and Pressure-Volume Loops
  3. Pressure-Volume Relations
  4. Preload
  5. Afterload
  6. Contractility
  7. Lusitropy
  8. Starling Curves
  9. Ventricular-Vascular Interactions Analyzed on the Pressure-Volume Diagram
  10. Right Ventricular Mechanics
  11. Atrial Mechanics
  12. Invassive Assessment of Pressure-Volume Relations
  13. Noninvassive Assessment of Pressure-Volume Relations

Get Part I of Harvi

Part II. Advanced Physiological Principles

  1. Normal Valve Function and Flow Patterns
  2. The Pericardium and Ventricular Interactions
  3. Excitation-Contraction Coupling
  4. Determinants of Myocardial Oxygen Consumption
  5. Basics of Myocardial Metabolism
  6. Regulation of Coronary Blood Flow
  7. Basics of Cardiovascular Receptor Biology and Pharmacology
  8. Autonomic Control of the Circulation

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Part III. Pathophysiology, Disease States and Therapeutics

  1. Mitral Regurgitation
  2. Mitral Stenosis
  3. Aortic Regurgitation
  4. Aortic Stenosis
  5. Pulmonary Valve Diseases
  6. Tricuspid Valve Diseases
  7. Atrial Fibrillation
  8. Ventricular Tachycardias
  9. Stable Coronary Artery Disease and Stress Testing
  10. Acute Coronary Syndromes
  11. Acute Pulmonary Edema
  12. Cardiogenic Shock
  13. Chronic Heart Failure with Reduced Ejection Fraction (HFrEF)
  14. Hypertrophic Cardiomyopathies
  15. Restrictive Cardiomyopathies
  16. Heart Failure with Hypertension and Preserved Ejection Fraction (HFpEF)
  17. Pulmonary Artery Hypertension
  18. Diseases of the Pericardium
  19. Hemodynamics and Cardiovascular Considerations During Pregnancy and Birth

Part III is Coming Soon

Part IV. Mechanical Assist Devices

  1. Intraaortic Balloon Pumps
  2. Extracorporial Left Atrial-to-Arterial Support
  3. Extracorporial Right Atrial-to-Aortic Support
  4. Transvalvular (acute) Left Ventricular-to- Aortic support
  5. Implanted (chronic) Left Ventricle-to-Arterial support
  6. CImplanted (chronic) Left Atrial-to- Arterial Support
  7. Chronic Heart Failure with Preserved Ejection Fraction (HFpEF)
  8. Right Ventricular Support

Part IV is Coming Soon

the story of harvi

Our Mission

Our mission is to help educate the scientific and medical cardiovascular community involved in research and patient care on the importance and virtues of assessment of heart function and hemodynamics through an approach based on pressure-volume analysis.